The University of Manitoba campuses are located on original lands of Anishinaabeg, Cree, Ojibwe-Cree, Dakota, and Dene peoples, and on the National Homeland of the Red River Métis. More
Heart Disease
Guidelines
American Heart Association. Guidelines Resource Center. (2020).
Jeejeebhoy F, et al. Cardiac Arrest in Pregnancy: A Scientific Statement From the American Heart Association. Circulation. 2015; 132(18): 1747-73.
Barbera J, et al. Guidelines on the diagnosis and treatment of pulmonary hypertension: summary of recommendations. Arch Bronconeumol. 2018; 54(4): 205-215.
Beaser A, et al. Management of patients with atrial fibrillation. JAMA. 2019; 321(11): 1100-1.
Brunham L, et al. Canadian Cardiovascular Society position statement on Familial Hypercholesterolemia: Update 2018. Can J Cardiol. 2018; 34(12): 1553-1563.
Canadian Cardiovascular Society. Guidelines Library. (2020).
Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Screening for the presence of coronary artery disease. Canadian Journal of Diabetes. 2013; 37: 105-9.
CCS Atrial Fibrillation Guidelines Committee, et al. The 2014 Atrial Fibrillation Guidelines Companion: A Practical Approach to the Use of the Canadian Cardiovascular Society Guidelines. Canadian Journal of Cardiology. 2015; 31: 1207-18.
Dworzynski K, et al. Diagnosing and managing acute heart failure in adults: summary of NICE guidance. BMJ. 2014; 349.
Heart and Stroke Foundation of Canada. Guidelines.
Kantor P, et al. Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines. Canadian Journal of Cardiology. 2013; 29: 1535-52.
Macle L, et al. 2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation. Canadian Journal of Cardiology. 2018; 34(11): 1371-92.
Neumar R, et al. American Heart Association Response to the 2015 Institute of Medicine Report on Strategies to Improve Cardiac Arrest Survival. Circulation. 2015; 132: 1049-70.
Pearson D. Review of Clinical Guidelines for Cardiopulmonary Resuscitation. N C Med J. 2015; 76(4): 257-9.
Wong G, et al. 2019 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion. Canadian Journal of Cardiology. 2019; 35(2): 107-32.
Circumpolar Heart Disease
Allaire J, et al. Prevalence and determinants of hypertension in the adult Inuit population of Nunavik (northern Quebec, Canada). Can J Public Health. 2023.
Burgess J. Doctor to the North : thirty years treating heart disease among the Inuit. 2008.
Chateau-Degat M, et al. Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: Insights from baseline findings in the circumpolar Inuit Health in Transition cohort study. Can J Cardiol. 2010; 26(6):190-6.
DiNicolantonio J, et al. Markedly increased intake of refined carbohydrates and sugar is associated with the rise of coronary heart disease and diabetes among the Alaskan Inuit. Open Heart. 2017; 4(2).
Erber E, et al. Prevalence and risk factors for self-reported chronic disease amongst Inuvialuit populations. Journal of Human Nutrition and Dietetics. 2010; 23(suppl 1): 43-50.
Fodor J, et al. "Fishing" for the origins of the "Eskimos and heart disease" story: facts or wishful thinking? Can J Cardiol. 2014; 30(8): 864-8.
Fontaine LS, et al. Listening to First Nations women' expressions of heart health: mite achimowin digital storytelling study. 2019; 78(1).
Hahn M, et al. Wildfire smoke is associated with an increased risk of cardiorespiratory emergency department visits in Alaska. Geohealth. 2021; 5(5).
Howard B, et al. Cardiovascular disease prevalence and its relation to risk factors in Alaska Eskimos. Nutr Metab Cardiovasc Dis. 2010; 20(5): 350-358.
Hiratsuka V, et al. Cardiovascular disease risk factor screening among Alaska Native women: the traditions of the heart project. Int J Circumpolar Health. 2007; 66(Suppl 1): 39-44.
Hu x, et al. High selenium exposure lowers the odds ratios for hypertension, stroke, and myocardial infarction associated with mercury exposure among Inuit in Canada. Environ Int. 2017;102:200-206.
Hu X, et al. Inuit country food diet pattern is associated with lower risk of coronary heart disease. J Acad Nutr Diet. 2018; 18(7): 1237-48.
Hu X, et al. Mercury diminishes the cardiovascular protective effect of omega-3 polyunsaturated fatty acids in the modern diet of Inuit in Canada. Environ Res. 2017;152:470-7.
Hu X, et al. Prevalence of heart attack and stroke and associated risk factors among Inuit in Canada: A comparison with the general Canadian population. Int J Hyg Environ Health. 2019;222(2):319-26.
Hutchinson R, et al. Systematic review of health disparities for cardiovascular diseases and associated factors among American Indian and Alaska native populations. PLos One. 2014;9(1).
Knox M, et al. Recruitment best practices of a cardiovascular risk reduction randomised control trial in rural Alaska Native communities. Int J Circumpolar Health. 2020; 79(1).
Labonté M, et al. Population-based study of high plasma C-reactive protein concentrations among the Inuit of Nunavik. Int J Circumpolar Health. 2012;71.
Larsen T, et al. Whole blood mercury and the risk of cardiovascular disease among the Greenlandic population. Environ Res. 2018;164:310-5.
NCCIH. Understanding First Nations women's heart health. 2019.
Noel M, et al. Cardiovascular risk factors and subclinical atherosclerosis among Nunavik Inuit. Atherosclerosis. 2012;221(2):558-64.
Overvad M, et al. The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland. Sci Rep. 2020; 10(1):22081.
Pakseresht M, et al. Awareness of chronic disease diagnosis amongst family members is associated with healthy dietary knowledge but not behaviour amongst Inuit in Arctic Canada. Journal of Human Nutrition and Dietetics. 2010;23(Suppl. 1):100-9.
Prince S, et al. The state of affairs of cardiovascular health research in Indigenous women in Canada: A scoping review. Can J Cardiol. 2018;34(4):437-49.
Roin T, et al. Knowledge about heart failure and self-care persists following outpatient programme: a prospective cohort study from the Faroe Islands. 2019;78(1).
Senftleber N, et al. Omega03 fatty acids and risk of cardiovascular disease in Inuit: First prospective cohort study. Atherosclerosis. 2020;312: 28-34. (Please request full-text)
Trayhurn P. Obesity in the Inuit - Adipose tissue and ischaemic heart disease. Int J Circumpolar Health. 2009;68(5).
Tvermosegaard M, et al. Cardiovascular Disease Susceptibility and Resistance in Circumpolar Inuit Populations. Can J Cardiol. 2015;31(9):1116-23.
Heart Defects
Arbour L, et al. Congenital heart defects in Canadian Inuit: is more folic acid making a difference? Alaska Med. 2007;49(2 Suppl):163-6.
Arbour L, et al. The Genetics of Cardiovascular Disease in Canadian and International Aboriginal Populations. Can J Cardiol. 2015;31(9):1094-115.
Arbour L, et al. Heart defects and other malformations in the Inuit in Canada: a baseline study. Int J Circumpolar Health. 2004;63(3):251-66.
No Author Listed. Guidelines for the management of congenital heart diseases in childhood and adolescence. Cardiol Young. 2017;27(S3):s1-s105.
Overvad M, et al. The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland. Sci Rep. 2020;10(1).
Heart Disease and the Environment
Hu X, et al. Mercury diminishes the cardiovascular protective effect of omega-3 polyunsaturated fatty acids in the modern diet of Inuit in Canada. Environ Res. 2017;152:470-477.
Parajuli R, et al. Variation in biomarker levels of metals, persistent organic pollutants, and omega-3 fatty acids in association with genetic polymorphisms among Inuit in Nunavik, Canada. Environ Res. 2021; 200. (Please request full-text)
Singh K, et al. Association between environmental contaminants and health outcomes in indigenous populations of the Circumpolar North. Int J Circumpolar Health. 2014;73.
Valera B, et al. Cardiac autonomic activity and blood pressure among Inuit children exposed to mercury. Neurotoxicology. 2012;33(5):1067-74.
Valera B, et al. Environmental mercury exposure and blood pressure among Nunavik Inuit adults. Hypertension. 2009;54:981-6.
Fatty Acids
Alkazemi D, et al. Increased F3-Isoprostanes in the Canadian Inuit population could be cardioprotective by limiting F2-Isoprostane production. J Clin Endocrinol Metab. 2016; 101(9):3264-71. (Please request full-text)
Ebbesson S, et al. Fatty acids linked to cardiovascular mortality are associated with risk factors. Int J Circumpolar Health. 2015;74.
Ebbesson S, et al. Heart rate is associated with markers of fatty acid desaturation: the GOCADAN study. Int J Circumpolar Health. 2012;71.
La Rovere M, et al. The autonomic nervous system and cardiovascular disease: role of n-3 PUFAs. Vascul Pharmacol. 2015;71:1-10.
Nicholson T, et al. The role of marine n-3 fatty acids in improving cardiovascular health: a review. Food Funct. 2013;4(3):357-65.
Rudkowska I, et al. Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population. Nutr Metab (London). 2013;10:26.
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