| Background Question | Foreground Question |
| General Knowledge, broad | Specific |
| Asks who, what, where, how | Uses P,I,C,O format |
| More likely to be asked when our knowledge is limited | More likely to be asked when we're more experienced |
| Answered using a point-of-care tool or textbook | Answered in a database, like PubMed |
| P | Population/Problem | Identify the population or problem of the scenario |
| I | Intervention | Identify the main exposure or intervention of the scenario |
| C | Comparison | Identify the comparison to the intervention - if available |
| O | Outcomes | Identify what will be measured, improved, or effected in the scenario |
| Therapy/Prevention | Questions that are seeking answers to determine effect of treatments or effect of a preventative measure |
| Diagnosis | Questions that are seeking answers to determine effect of a diagnostic test or measure |
| Harm, Etiology, or Prevention | Questions that are determining causes of a disease or condition |
| Prognosis | Questions that are seeking to determine the clinical course or progression of a disease or condition |